abstract：:Iron pill gastritis has been shown to be associated with superficial gastric erosion and deposition of iron in lamina propria and gastric antral glands. However, iron absorption in gastric parietal and chief cells is rare. We present a case of a 62-year-old man with iron deficiency anemia. His past medical history is ...

journal_title：Annals of clinical and laboratory science

authors： Shafique K,Araujo JL,Veluvolu R,Cassai N,Desoto-Lapaix F,Pincus MR,Wieczorek RL

更新日期：2017-05-01 00:00:00

abstract：GOALS:This study aims to examine the effects of raising the reporting age for benign endometrial cells (BEC) on Papanicolaou (Pap) tests according to the 2014 3rd edition of the Bethesda System for Cervical Cytology, as well as the sequelae of the 2012 American Society of Colposcopy and Cervical Pathology (ASCCP) guide...

journal_title：Annals of clinical and laboratory science

authors： Morikawa LH,Tauchi-Nishi PS

更新日期：2017-05-01 00:00:00

abstract：:Hand, foot and mouth disease (HFMD) is a serious public health problem. Generally, it is considered that HFMD is mainly caused by enterovirus 71 (EV71) and coxsackievirus A16 (CVA16). Nevertheless, the incidence of HFMD caused by coxsackievirus A6 (CVA6) and coxsackievirus A10 (CVA10) has increased significantly and C...

journal_title：Annals of clinical and laboratory science

authors： He P,Li Y,Luo J,Wang H,Yan Y,Chen Z

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:This study aimed to investigate the prognostic value of lymph node ratio (LNR), number of removed lymph nodes (RLNs), and number of negative lymph nodes (NLNs) in Chinese patients with triple negative breast cancer. METHODS:The study cohort comprised 394 breast cancer patients with the triple negative subtyp...

journal_title：Annals of clinical and laboratory science

authors： Wang QX,Cai YF,Chen YY,Zhang W,Jin WX,Chen ED,Zhang XH,Li Q

更新日期：2017-01-01 00:00:00

abstract：:Previous studies have suggested that there is a disproportionally higher risk of infection following traumatic brain injury (TBI). This predisposition to infection may be driven by a poorly understood, brain-specific response in the immune system after TBI. However, there is a lack of studies that have fully character...

journal_title：Annals of clinical and laboratory science

authors： Wang JW,Li JP,Song YL,Zhao QH

更新日期：2017-01-01 00:00:00

abstract：:People of the Jehovah's Witness faith believe that they shall "abstain from blood." Because of this belief, we encounter the challenges from Jehovah's Witness patients who actively seek medical care for themselves and their children, but refuse the transfusion of blood products, which may result in increased morbidity...

journal_title：Annals of clinical and laboratory science

authors： Bai Y,Castillo BS,Tchakarov A,Escobar MA,Cotton BA,Holcomb JB,Brown RE

更新日期：2016-12-01 00:00:00

abstract：:Oxidative stress plays a pivotal role in the pathogenesis of multiple sclerosis (MS). Inactivating polymorphism of genes encoding detoxification enzymes, such as NQO1 and GSTP1 could influence susceptibility to MS. The monoclonal antibody natalizumab is an effective treatment in MS. Natalizumab's efficacy in MS patien...

journal_title：Annals of clinical and laboratory science

authors： Alexoudi A,Zachaki S,Stavropoulou C,Gavrili S,Spiliopoulou C,Papadodima S,Karageorgiou CE,Sambani C

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Various assays for detecting high-risk human papillomavirus (HR HPV) have been introduced recently, including the Abbott RealTime High-Risk HPV assay. We sought to compare the performance of Abbott PCR to Hybrid Capture 2 for the detection of HR HPV. METHODS:A total of 941 cervical swab specimens were obtai...

journal_title：Annals of clinical and laboratory science

authors： Ko K,Yu S,Lee EH,Park H,Woo HY,Kwon MJ

更新日期：2016-09-01 00:00:00

abstract：:This study was to examine the inhibitory effect of matrine on the proliferation and metastasis of gastric cancer cells, and to explore the possible mechanisms involved in these processes. MTT was used to evaluate the proliferation ability of SGC7901 cells. A two and three-dimensional cell migration assay were performe...

journal_title：Annals of clinical and laboratory science

authors： Peng X,Zhou D,Wang X,Hu Z,Yan Y,Huang J

更新日期：2016-09-01 00:00:00

abstract：:Transforming growth factor beta (TGF-β) plays an important role in many pathophysiological conditions, including cancer. The level of TGF-β in patients with differentiated thyroid cancer (DTC) has not been examined so far. The aim of this study was to measure TGF-β concentration in serum samples and in PHA-stimulated ...

journal_title：Annals of clinical and laboratory science

authors： Zivancevic-Simonovic S,Mihaljevic O,Mihajlovic D,Milosevic-Djordjevic O,Jovanovic Z,Mijatovic-Teodorovic L,Colic M

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Long-term use of hormones and immunosuppressive agents is necessary for treating polymyositis (PM)/dermatomyositis (DM) but may cause liver damage. At what point do the costs of treatment outweigh the benefits, and how will the breakeven point be determined? METHODS:Serum muscle enzyme changes in 93 PM/DM p...

journal_title：Annals of clinical and laboratory science

authors： Shi Q,Niu J,Huang X,Pu C

更新日期：2016-05-01 00:00:00

abstract：:Spindle cell variant of cutaneous B-cell lymphoma is a rare entity which poses a diagnostic difficulty. The differential diagnosis of cutaneous spindle cell lesions is broad, and often includes sarcoma, carcinoma, and melanoma. Lymphoma with spindle cell morphology is frequently only considered after exclusion of more...

journal_title：Annals of clinical and laboratory science

authors： Forcucci J,Ralston J,Lazarchick J

更新日期：2016-04-01 00:00:00

abstract：:Reactive amyloid deposits consist of amyloid A (AA) proteins, the degradation products of serum amyloid A (SAA). Since the most common species of AA is the amino terminal portion produced by cleavage between residues 76 and 77 of SAA (AA76), the presence of AA76 in tissues could be a consequence of AA amyloid depositi...

journal_title：Annals of clinical and laboratory science

authors： Sato J,Okuda Y,Kuroda T,Yamada T

更新日期：2016-04-01 00:00:00

abstract：:Low-grade fibromyxoid sarcoma (LGFMS) is a rare soft-tissue neoplasm with a deceptively benign histological appearance and low-grade malignant potential which is often mistaken for other reactive or benign lesions. It most frequently harbors balanced t(7;16) translocation, and leads to the fusion of the FUS and CREB3L...

journal_title：Annals of clinical and laboratory science

authors： Chien YC,Károlyi K,Kovács I

更新日期：2016-01-01 00:00:00

abstract：:Diabetic cardiomyopathy (DCM) is associated with functional and structural pathological changes such as hypoxia and inflammation. Hypoxia-inducible factor-1α(HIF-1α) is a core transcription factor for restoring homeostasis in intracellular oxygen and has a crucial role in preventing the development of DCM. However, th...

journal_title：Annals of clinical and laboratory science

authors： Lin Y,Tang Y,Wang F

更新日期：2016-01-01 00:00:00

abstract：:Hematological malignancies exhibit many clinical presentations, from ambiguous systemic symptoms to rapid multi-organ failure. By identifying common clinical, laboratory, and autopsy findings in patients with a hematological malignancy, living patients may be diagnosed and treated earlier. We retrospectively reviewed ...

journal_title：Annals of clinical and laboratory science

authors： Dierksen J,Buja LM,Chen L

更新日期：2015-10-01 00:00:00

abstract：CONTEXT:Myotonic dystrophies (DMs) are a group of autosomal dominant neuromuscular disorders which are caused by large CTG/CCTG-repeat expansions in untranslated regions of DMPK/ZNF9 gene. The "phenotypic overlap" in DMs creates complication in distinguishing patients with DM1 from patients with DM2 and underscores the...

journal_title：Annals of clinical and laboratory science

authors： Meng YX,Shen HR,Zhao Z,Bing Q,Li N,Hu J

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:The microscopic and chemical analysis of urine is essential for the diagnosis of patients with urinary tract infections (UTI). Quantitative urine culture is the 'gold standard' method for the diagnosis of UTI, but it is labour-intensive and time consuming. The DongJiu 8602 is a new automated urinalysis system...

journal_title：Annals of clinical and laboratory science

authors： Kocer D,Sariguzel FM,Ciraci MZ,Karakukcu C,Oz L

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Carbohydrate antigen series biomarkers in cerebrospinal fluid (CSF) are important for the diagnosis of brain metastasis and meningeal carcinomatosis. Its relationship with CSF and serum in non-neoplastic diseases may be beneficial for earlier diagnosis and treatment. MATERIALS AND METHODS:161 pairs of CSF a...

journal_title：Annals of clinical and laboratory science

authors： Shi Q,Tian C,Huang X,Pu C

更新日期：2015-10-01 00:00:00

abstract：:Chemokines are low-molecular-weight chemotactic proteins that regulate the trafficking of leukocytes to inflammatory sites and may recruit inflammatory cells to the epidermis. Chemokines are produced by many immune cells such as macrophages, mast cells, T lymphocytes and others, in response to pro-inflammatory stimuli...

journal_title：Annals of clinical and laboratory science

authors： Shaik-Dasthagirisaheb YB,Conti P

更新日期：2015-07-01 00:00:00

abstract：:The Access(®) soluble transferrin receptor (sTfR) is considered the world's first automated chemiluminescence immunoassay. In this study, the diagnostic utility of this and other tests for serum iron were evaluated by studying their interrelationships with inflammation. A total of 367 patients with anemia (iron defici...

journal_title：Annals of clinical and laboratory science

authors： Shin DH,Kim HS,Park MJ,Suh IB,Shin KS

更新日期：2015-07-01 00:00:00

abstract：:Mucoepidermoid carcinoma of the lung is exceedingly rare. Our case involves a 58-year-old male who presented with shortness of breath, dysphagia, and weight loss. He denied ever smoking. Chest x-ray revealed trapped lung, and CT demonstrated a right bronchial mass. Diagnosis of lung carcinoma was made by bronchoscopic...

journal_title：Annals of clinical and laboratory science

authors： Thomas D,Modi Y,Dorai B,Guron G

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:An increasing number of studies have pointed out the side effects of valproic acid (VPA), an antiepileptic drug used for the treatment of seizures in children and adults. The aim of this study is to evaluate whether VPA interferes with oxidative metabolism in the heart and whether edaravone, the novel free r...

journal_title：Annals of clinical and laboratory science

authors： Emekli-Alturfan E,Alev B,Tunali S,Oktay S,Tunali-Akbay T,Ozturk LK,Yanardag R,Yarat A

更新日期：2015-04-01 00:00:00

abstract：:Plasma cell granuloma (PCG) is a relatively rare, mass-forming lesion comprised of polyclonal plasma cells set in a background of storiform fibrosis and spindle cell proliferation. While uncommon, this lesion may occur within any site and should be included in the list of differential diagnoses for plasma cell neoplas...

journal_title：Annals of clinical and laboratory science

authors： Forcucci J,Butler-Williams S,Miller N,Lazarchick J

更新日期：2015-04-01 00:00:00

abstract：:Human amniotic-derived cells (hAMCs) have recently raised interest for their differentiation capability and immunomodulatory properties. To assess the feasibility of hAMCs therapeutic treatment during fetal development, we explored the localization of cells derived from the human amniotic membrane in rat organs after ...

journal_title：Annals of clinical and laboratory science

authors： Burrai GP,Antuofermo E,Farigu S,Cargnoni A,Bonassi P,Pasciu V,Demontis MP,Parolini O,Varoni MV

更新日期：2015-04-01 00:00:00

abstract：:Mosaic variegated aneuploidy (MVA) is a recessive condition characterized by mosaic aneuploidies, predominantly trisomies and monosomies, involving multiple chromosomes and tissues. The phenotype of MVA syndrome includes severe microcephaly and growth deficiency, central nervous system anomalies, mental retardation, m...

journal_title：Annals of clinical and laboratory science

authors： Cho CH,Oh MJ,Lim CS,Lee CK,Cho Y,Yoon SY

更新日期：2015-01-01 00:00:00

abstract：:In this study, we investigated the relationship between thyroid function and serum uric acid (UA) levels in subjects without overt thyroid dysfunction. A total of 6,085 patients were included in this cross-sectional study. Free thyroxine (FT4) levels were positively and linearly associated with serum UA levels (p<0.00...

journal_title：Annals of clinical and laboratory science

authors： Ye Y,Gai X,Xie H,Jiao L,Zhang S

更新日期：2015-01-01 00:00:00

abstract：:Adenoid cystic carcinoma (ACC) is a rare cervical malignancy, and its coexistence with other malignancies in the uterine cervix is extremely rare. Here, we present a case of coexistence of ACC and invasive squamous cell carcinoma (SCC) of the uterine cervix, as well as a literature review. A 68-year-old Chinese woman ...

journal_title：Annals of clinical and laboratory science

authors： Shi X,Chang X,Wu H,Ren X,Liu T,Bui MM

更新日期：2014-10-01 00:00:00

abstract：:This study was designed to explore the association between the G protein-coupled receptor 109A (GPR109A) expression in peripheral blood leukocytes (PBLs) and type 2 diabetes (T2DM) and to discuss the regulation of inflammatory factors by GPR109A signaling. GPR109A signaling has been confirmed to be associated with hom...

journal_title：Annals of clinical and laboratory science

authors： Liu F,Fu Y,Wei C,Chen Y,Ma S,Xu W

更新日期：2014-10-01 00:00:00

abstract：:M. Tuberculosis (MTB) is an obligate human parasite even though humans are more resistant than any of the animals used for study. It is a human parasite because only humans develop post primary tuberculosis (TB) in their lungs that mediates transmission of infection to new hosts. The extreme paucity of human lung tiss...

journal_title：Annals of clinical and laboratory science

authors： Hunter RL,Actor JK,Hwang SA,Karev V,Jagannath C

更新日期：2014-10-01 00:00:00

abstract：:We report the case of a 45 year old man who came to Emergency Room of Polyclinic for sudden onset of localized ecchymosis and widespread hematomas. He was subjected to blood count and first level investigations to assess coagulation. Based on the results, second level investigations were performed. Endoscopy of the ga...

journal_title：Annals of clinical and laboratory science

authors： Agnello L,Bellia C,Lo Coco L,Vitale S,Coraci F,Bonura F,Gnoffo R,Napolitano M,Caruso A,Bivona G,Lo Sasso B,Ciaccio M

更新日期：2014-07-01 00:00:00

abstract：:HbA2' (also called Hb B2) is the most common delta-globin chain defect and is reported to occur in 1-2% of the African American population. The major clinical significance of HbA2' is that the failure to detect it might lead to an underestimation of the total HbA2, leading to failure to diagnose β-thalassemia minor. I...

journal_title：Annals of clinical and laboratory science

authors： Oleske DA,Huang RS,Dasgupta A,Nguyen A,Wahed A

更新日期：2014-07-01 00:00:00

abstract：:Acne vulgaris is a common dermatological disorder with a multifactorial pathogenesis. Oxidative status has been implicated in the pathogenesis of several skin diseases, including acne. This study was aimed to investigate the levels of oxidative stress biomarkers in acne vulgaris patients with varying severities. The s...

journal_title：Annals of clinical and laboratory science

authors： Al-Shobaili HA

更新日期：2014-04-01 00:00:00

abstract：:Infection with atypical mycobacteria (MAC) is a well-known complication of AIDS that typically occurs only in people with advanced immunodeficiency. We studied tissues from 13 patients with HIV and atypical mycobacterial infection who died in St Petersburg Russia from 2009-2012. Three patterns of disease were identifi...

journal_title：Annals of clinical and laboratory science

authors： Mayskaya MU,Otten TF,Ariel BM,Fedotova EP,Hunter RL,Nasyrov RA

更新日期：2014-04-01 00:00:00

abstract：:A fifteen-year-old girl was treated with isoniazid (INH) for latent tuberculosis infection (LTBI), and subsequently developed epigastric pain, vomiting, and jaundice after three months of treatment. Acute fulminant hepatic failure was diagnosed. INH was stopped, and she received N-acetyl cysteine and Vitamin K. Liver ...

journal_title：Annals of clinical and laboratory science

authors： Gourishankar A,Navarro F,Debroy AN,Smith KC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Clostridium difficile is one of the most common causes of nosocomial diarrhea, and diagnostic methods for detecting C. difficile infection have shifted from conventional to more recent molecular techniques. This study aimed to compare the performance of two molecular assays (Meridian Illumigene™ and AdvanSur...

journal_title：Annals of clinical and laboratory science

authors： Soh YS,Yang JJ,You E,La Jeon Y,Kim MJ,Nam YS,Cho SY,Park TS,Lee HJ

更新日期：2014-01-01 00:00:00

abstract：:Thiols have been of enduring interest for many years because of their role in biological and pharmacological processes. Monitoring of total thiols content is very important in order to understand their function in living organisms. This paper describes the spectrophotometric method for the determination of total thiol...

journal_title：Annals of clinical and laboratory science

authors： Chwatko G

更新日期：2013-10-01 00:00:00

abstract：:We present an adult autopsy case of primary hyperoxaluria type 1. Diagnosis was established with skin biopsy and subsequent genetic analysis one month prior to death. At autopsy, calcium oxalate crystals refringent to polarized light were found systemically. Interestingly, however, calcium oxalate crystals were not id...

journal_title：Annals of clinical and laboratory science

authors： Falk N,Castillo B,Gupta A,McKelvy B,Bhattacharjee M,Papasozomenos S

更新日期：2013-07-01 00:00:00

abstract：:A considerable variabilility in the effects of sample handling on NK cytotoxicity has been observed. Using flow cytometry, NK cytotoxicity assays and lymphocyte subset analysis of Ficoll-Hypaque-separated peripheral blood mononuclear cells (PBMCs) isolated from whole blood stored under various conditions were performe...

journal_title：Annals of clinical and laboratory science

authors： Kim DW,Jang YY,Shin MG,Shin JH,Suh SP,Ryang DW,Yoon M,Lee JJ,Kim SK,Cho D

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:We compared the AdvanSure hepatitis B virus real-time polymerase chain reaction (AdvanSure HBV) kit with three other HBV DNA quantification assays and evaluated its performance. METHODS:The AdvanSure HBV real-time PCR assay was compared with the Abbott RealTime HBV Quantification Kit, the COBAS TaqMan HBV T...

journal_title：Annals of clinical and laboratory science

authors： Kim H,Shin S,Oh EJ,Kahng J,Kim Y,Lee HK,Kwon HJ

更新日期：2013-04-01 00:00:00